KJ1020
Organic Chemistry
Last taught 2021
Spring
Trondheim
Norwegian
About this course
Content
Introduction to organic reaction and their mechanisms, nomenclature and conformations of alkanes and cycloalkanes, stereochemistry, substitution (SN1, SN2 ) and elimination (E1/E2) reactions of alkyl halides, addition reactions of alkenes and alkynes,synthesis and reactions of alcohols and ethers, oxidation-reduction and Grignard compounds,conjugated unsaturated systems, aromatic compounds, electrophil aromatic sustitution reactions, nucleophilic addition to the carbonyl group of aldehyds and ketones, carboxylic acids , their derivatives and nucleophilic addition-elimination reaction,reactions at the a-carbon atom of carbonyl compounds (enolater), condensation and conjugate addition reactions of carbonyl compounds, synthesis and reactions of amines, arenediazonium salts, nucleophilic aromatic substitution of phenols and aryl halides, introduction to carbohydrates, introduction to amino acids, introduction to lipids
Learning outcomes
After completing this course the student will, in relation to the content of the subject:
- be able to understand and communicate nomenclature and structure of organic chemical compounds
- know basic principles for reactions in organic chemistry
- be able to account for and derive mechanistic features of the reactions
- be able to predict competing reactions
- be able to name central reactions
- have a basic knowledge of how functional groups affect electron density, properties and reactivity in organic compounds
- be able to estimate pKa values for carboxylic acids, amines, alcohols and ketones in the presence of different functional groups
- The HSE lecture will give the students a basic understanding in how to behave and work safely in the laboratory.
Teaching methods
The course consists of lectures (4 hours per week), theoretical excercises (2 hours per week, 67% of exercises must be accepted) and a laboratory course. As a part of the compulsary laboratory course is a compulsary HSE lecture. The HSE lecture will be given within the first two weeks of the semester. Students that miss this HSE lecture will not get access to the laboratory course. In the laboratory course students learn the basic laboratory techniques and perform a certain number of syntheses to illustrate the theorie. The laboratory course (100 hours) must be approved before the final examination.