Innføring i molekylærmedisin

The lectures will cover the organisation and major features of the human genome, such as replication, gene expression, epigenetics and the role of non-coding RNA. Consequences of mutations and polymorphisms, inherited diseases and molecular aspects of major common diseases, such as cancer, diabetes, vascular and coronary disease are central topics. Infectious diseases and treatment, applied bioinformatics, drug development and use of stem cells and organoids will also be addressed.

Knowledge

The candidate can

• describe the organization of the human genome and its functional regulation, including replication and maintenance, gene expression, epigenetic modifications, and the role of non-coding RNA
• explain the impact of genes and environment on disease development
• describe how microorganisms cause infection, the mechanisms of action of antimicrobial drugs and how antimicrobial resistance develops
• describe important methods in molecular medicine, including gene editing, the use of stem cells and organoids, and the stages of drug development
• explain how normal cellular processes change, fail, or get destroyed in common complex diseases such as cancer, diabetes, and cardiovascular and brain-related disorders

Skills

The candidate can

• apply and interpret data from simple bioinformatic tools
• collect and evaluate relevant information from articles within molecular medicine

General competence

The candidate can

• discuss and orally present scientific papers within the field of molecular medicine (in English)

The curriculum of the course is defined by learning objectives. Lectures, team-based learning sessions and article presentations are included. The language of instruction and examination is English, and the exam must be answered in English.