Heterocyclic Chemistry

The course deals with heterocyclic chemistry in a broad perspective. Emphasis is given on the most important heterocyclic systems, such as pyridines, quinolines, isoquinolines, pyrroles, furanes, tiophenes, indoles, pyrimidines, purines, imidazoles, aziridines and oxiranes. For each group, ring synthesis, chemical properties and characteristic reactions will be discussed. Aromaticity applied to heterocyclic compounds, general methods for ring synthesis (by a number of cyclisation and cycloadditon reactions) as well as different systems for nomenclature will be presented.

The course aims at giving a fundamental theoretical understanding of heterocyclic chemistry, including alternative general methods for ring synthesis and application of such methods for the preparation of specific groups of heterocyclic systems. The student will get familiar with particular properties and reactions for the most important heterocycles as well as different systems of nomenclature.

Assemblies (2 hrs per week); the students prepare individual presentations of specific topics to be discussed.