Molecular Mechanisms of Toxicology

The course will be given every second year, next time autumn 2017.
The course gives students an understanding of how cells and organisms respond to chemical agents: xenobiotic metabolism; oxidative stress; inflammation; nuclear receptor-mediated toxicity; DNA damage inflicted by toxic chemicals and carcinogenic compounds; the role of signal transduction systems and gene regulation; cell cycle regulation; DNA repair; apoptotic and necrotic cell death; gene – environment interactions, genetic susceptibility.

Enhance the student`s understanding of the harmful interactions between environmental agents and biological targets aiming at molecular mechanisms and pathways underlying these effects.

Lectures. Intensive course 7-8 weeks
Exam: written. In case of few students the written exam can be replaced by an oral examination. The course will be given in English if necessary.